A cell's inability to make histone proteins would be most probable to lead to its DNA being unable to fit into its nucleus.
Therefore, it is probable that DNA wouldn't be capable of being stored inside the cellular nuclei effectively if a cell was unable to generate histone proteins. The telomerase enzyme facilitates the replication of chromosomal ends. The telomere sequence at these ends will shrink as a result of the enzyme's decreased activity. The cell will age as a result, and its capabilities will be lost. With each round of mitosis, its chromosome length would decrease, resulting in defective cells. With each round of mitosis, its chromosome length would decrease, resulting in defective cells. Without mitosis, there wouldn't be any cell division or growth. The fact that genetic code cannot be carried on is most essential.
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