When ion channels in cell membrane open or close, it causes depolarization and hyperpolarization by changing which ions can enter or leave the cell.
Positive ions are drawn to the "negative" side of the membrane, while negative ions are drawn to the "positive" side, creating a potential gradient known as membrane potential that compels ions to passively migrate in one way.
A sudden increase in membrane potential that opens na+ in the cell membrane and causes a significant influx of sodium ions causes depolarization. Rapid potassium channels inactivation and a significant potassium ion outflow brought on by active potassium channels cause membrane repolarization.
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