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An area of DNA called a promoter is where a gene first starts to transcribe. Because they control how RNA polymerase binds to DNA, promoters are crucial components of expression vectors.

Define promoter region.

The sense or coding strand of the transcribed gene is positioned adjacent to and typically upstream (5') of the promoters. They are between 100 and 1000 base pairs long. Coding strand refers to the DNA strand that encodes codons and whose sequence corresponds to the mRNA transcript generated. The antisense strand, which is often referred to as the template strand or non-coding strand, is translated by the RNA polymerase.

Response elements are DNA sequences found in promoter regions that provide RNA polymerase and transcription factors with dependable binding sites. RNA polymerase recruitment, DNA transcription control, and mRNA regulation are all carried out by proteins known as transcription factors.

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