Answer:
The Middle Colonies like New York and Pennsylvania had more cities because they were the most populated, and the most cosmpolitan. Industry, and trade were promoted in these colonies, as well as a diverse population because there was a higher degree of tolerance for other religious denominatios. Maryland for example, was a haven for Catholics in Colonial America.
Southern Colonies like Virginia or South Carolina were the most rural. This was because the economy of these colonies was based on agriculture, either in the form of large cash crop plantations that were worked by African American slaves, or in the form of small, subsistance farms in the backcountry (Appalachia), which were settled by poor Europeans, mainly coming from Scotland and Northern Ireland (Ulster).