When the pH falls below 7.35, a state of acidosis exists.
The normal pH in the mammals arterial blood is between 7.35 and 7.50, so acidosis occurs when arterial pH falls below 7.35. Acidosis is a process causing increased acidity (increased hydrogen ion or proton H⁺ concentration) in the blood and other body tissues.
Alkalosis occurs at a pH over 7.45.