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During infection,
c. diphtheriae grows and multiplies within the upper respiratory tract. as each bacterial cell prepares for division the chromosome must be replicated so that each daughter cell receives a copy of the genetic information. the following statements summarize the major steps in replicating the bacterial chromosome. arrange the statements in the correct order to describe the process of replication of the leading strand.

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zebrius
The first event would be the unwinding of the double-stranded DNA by an enzyme called helicase. The next step will be the binding of specific proteins to the single strands, in order to stabilize them. Then the enzyme primase (which is a specific type of RNA polymerase) will synthesize an RNA primer. This RNA primer will be complementary to the DNA and will act as a template. This step is important because the enzymes that catalyze the formation of DNA strands, can only attach new nucleotides to an existing strand of nucleotides. Therefore, the next step will be the formation of a nucleotide strand by the DNA polymerase. DNA polymerase catalyzes formation of a sugar-phosphate bond neighboring nucleotides. Finally, hydrogen bonds are formed between the complementary bases. This will bind the two strands of nucleotides and create the double-stranded DNA molecule.
annyksl

Hello. You forgot to put the information out of order. The information is:

"DNA polymerase catalyzes formation of a sugar-phosphate bond neighboring nucleotides .

Proteins bind to the DNA in order to stabilize the single strands

Primase synthesizes an RNA primer

Hydrogen bonds form between the complementary bases

Double stranded DNA is unwounded by helicase"

Answer:

  1. Double stranded DNA is unwounded by helicase
  2. Proteins bind to the DNA in order to stabilize the single strands
  3. Primase synthesizes an RNA primer
  4. DNA polymerase catalyzes formation of a sugar-phosphate bond neighboring nucleotides
  5. Hydrogen bonds form between the complementary bases

Explanation:

First, it is necessary that the two strands of DNA are unrolled, so that the process can be started. This unwinding happens with the action of the helicase enzyme that breaks the hydrogen bonds between the nucleotides.

This causes the two strands of DNA to separate and since DNA is a very unstable molecule, the two strands need to be stabilized. This happens with the binding of some proteins.

The DNA polymerase then approaches each strand and begins the process of forming new strands by forming nucleotides neighboring the sugar-phosphate bond.

Once new strands are formed, it is possible for new hydrogen bonds to form between the nucleotides of an old strand with a new strand.

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