A tricyclic antidepressant has been prescribed to a 77-year-old client whose current medication regimen includes omeprazole, captopril, calcium carbonate, alendronate, and warfarin. what assessment should the nurse prioritize when monitoring the client for drug-drug interactions?

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13-03-2018
Biology

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A tricyclic antidepressant has been prescribed to a 77-year-old client whose current medication regimen includes omeprazole, captopril, calcium carbonate, alendronate, and warfarin. what assessment should the nurse prioritize when monitoring the client for drug-drug interactions?

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haleymabile haleymabile · Answer 1 · 2018-03-23T04:19:20+01:00

Monitor the client closely for bleeding and review coagulation indices when available.

Combining TCAs with warfarin creates a risk for bleeding, which should be addressed in the nursing care plan. There is no known interaction between TCAs and calcium supplements or bisphosphonates that would create a risk for hypocalcemia. TCAs do not heighten the risk of gastroesophageal reflux. TCAs can affect blood pressure, but this is unrelated to any known drug-drug interactions.

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Larus Larus · Answer 2 · 2019-08-05T09:13:43+02:00

Answer:

There is a need to monitor closely for bleeding and review coagulation indices when accessible.

Explanation:

Combining warfarin with TCAs develops a threat for bleeding that should be assessed in the nursing care plan. There is no familiar association between the calcium supplements or bisphosphonates and TCAs, which would develop a threat of hypocalcemia. The TCAs do not elevate the threat of gastroesophageal reflux. The TCAs can influence blood pressure, however, this is not associated with any known drug-drug associations.