The excretory system and the circulatory system are the two that interact with one another and expel the waste product carbon dioxide.
The excretory system expels carbon dioxide, water, and other harmful substances from the body. It is mediated by a pair of kidneys that is considered the major organ for excretion.
The Circulatory system replaces the carbon dioxide from the blood with that oxygen which is essential for cellular metabolic activity.
Therefore, the excretory system and the circulatory system are the two that interact with one another and expel the waste product carbon dioxide.
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