The cross between a man with heterozygous Type A blood and a woman with Type O blood will produce Type A blood and Type O blood individuals at a 1:1 ratio (i.e., 1/2 each type).
Human blood type is determined by three different alleles: A, B and O.
The A and B alleles are codominant in heterozygous individuals, while both alleles (A and B) are dominant over O.
In consequence, individuals who have an AO genotype exhibit an A phenotype, while individuals who have an OO genotype exhibit an O phenotype.
In this case, the male can pass to their offspring gametes containing either the A allele or O allele; while the mother only can pass to their offspring the O allele.
In consequence, the filial 1 (F1) generation of this cross is:
Punnett square (F1)
A O
O 1/2 AO 1/2 OO
In conclusion, the cross between a man with heterozygous Type A blood (genotype AO) and a woman with Type O blood (genotype OO) will produce Type A blood (genotype AO) individuals and Type O blood (genotype OO) individuals at a 1:1 ratio.
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