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Cytoskeleton
Scaffolding

Microtubules are one, responsible for the framework and acts as a skeleton of the cell –cytoskeleton needs proteins, also cytoplasm and other organelles of the cell.
Proteins play a role in the physical make-up of a cell or acts as a cytoskeleton –maintains cell shape and figure. These proteins plays different roles and works with nucleic acids and other macromolecules in the cells including cell cycle, cell adhesion, immune response and cell indicators. 

The cytoskeleton is responsible  for cell shape, motility, of the cell as a whole and motility of organelles within a cell.  The cytoskeleton is extremely dynamic which is necessary for cells to be able to change shape , complete cell division, or migrate.The cytoskeleton is the frame work of the cell. It is highly organized and also flexible. It  does not seem the same  as the human skeleton but some parts can act like our bones  and other parts like our muscles.