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Monogenetic disorders are caused by a mutation in a single gene. The mutation may be present on one or both chromosomes (one chromosome inherited from each parent). Examples of monogenic disorders are: sickle cell disease, cystic fibrosis, polycystic kidney disease, and Tay-Sachs disease.
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Monogenetic disorders or Mendelian disease is caused by changes or mutations that happen in the DNA sequence of a single gene.

What is a Mendelian disease?

Monogenic or Mendelian diseases are conditions in which the primary cause can be attributed to a single defined genetic variant, that is, it affects a single gene.

Examples of monogenic diseases are:

  • Sickle cell anemia. (or depranocytosis)
  • Cystic fibrosis.
  • Batten's disease.
  • Huntington's disease (chromosome 4).
  • Marfan syndrome.
  • hemochromatosis.
  • Alpha-1 antitrypsin deficiency.
  • Duchenne muscular dystrophy.

With this information, we can conclude that monogenetic disorders or Mendelian disease are caused by changes or mutations that occur in the DNA sequence of a single gene.

Learn more about DNA in brainly.com/question/264225