The correct answers are 2) almost all American Indians died of disease and starvation and 3) many American Indians were killed and forced to move to reservations.
The effect of the Manifested destiny on the American Indian population was that almost all American Indians died of disease and starvation and many American Indians were killed and forced to move to reservations.
Some years after the end of the Revolutionary War, the government of the United States passed some pieces of legislation to determine how to deal with native American Indians. These were the Northwest Ordinance of 1787, the Indian Trade and Intercourse of 1790, and the Commerce Clause of the US Constitution. By 1840, thousands of Indians had been removed from their territories. The White people knew that those territories meant money and profits in their hands. Among the tribes affected were the Cherokee, Chickasaw, Choctaw, and Creek. So yes, The effect of the Manifested destiny on the American Indian population was that almost all American Indians died of disease and starvation and many American Indians were killed and forced to move to reservations.
