Which of the following statements is incorrect regarding Gilenya (fingolimod)?
1) First dose observation is required to monitor heart rate, BP, and EKG for 6 hours following dose
2) Patients should have their eyes examined prior to and 3-4 months after initiating treatment due to risk of macular edema
3) Patient should be educated on the symptoms of Progressive Multifocal Leukoencephalopathy (PML) prior to initiating therapy
4) It is necessary to repeat first dose observation if a patient has missed 2 weeks of Gilenya