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The Columbian Exchange was the widespread transfer of plants, animals, culture, human populations, technology, and ideas between the Americas and the Old World in the 15th and 16th centuries, related to European colonization and trade after Christopher Columbus's 1492 voyage.
The Columbian Exchange refers to a period of cultural and biological exchanges between the New and Old Worlds.  Exchanges of plants, animals, diseases and technology transformed European and Native American ways of life.