An intron mutation would have no impact on a protein's amino acid sequence unless it happened inside the 5′, 3′, or branch point splices, which are eliminated before translation.
A point mutation or even a sizable deletion in the intron would probably not appreciably lower the expression of the gene unless splicing was affected since the intron regions that affect mRNA accumulation are redundant and scattered.
a genetic change in the DNA sequence that takes place at the exon-intron boundary (splice site).
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