After puberty and during the ovarian cycle the secondary oocyte pauses in Metaphase II
- The paired chromosomes align during metaphase II. Anaphase II: The chromatids split at the centromere and migrate to opposite poles along the spindle fibers.
- Telophase II: The cells pinch in the middle and divide once more. The end result is four cells, each containing half of the genetic material found in the original.
- The centromeres of the paired chromatids align along the equatorial plate in both cells during metaphase II.
- The chromosomes then separate at the centromeres during anaphase II. The spindle fibers pull the separated chromosomes toward the cell's poles.
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