EXCEPT for leukotrienes and histamine, all of the following increase blood vessel permeability.
Histamine and leukotrienes are chemical compounds that cause inflammation by stimulating it. Eicosanoids, like leukotrienes, are important in the pathogenesis of inflammation. They are produced in leucocytes using 5-lipoxygenase to convert arachidonic acid into them. Histamine is released by the body in response to an allergen, such as pollen or animal dander, which causes inflammation at the point of contact. This process is a crucial component of the immune response of the body.
It is a collection of negative responses delivered by the typical safe framework, such as hypersensitivities and autoimmunity. They are commonly referred to as an over-response of the resistant framework, and these responses can be harmful, awkward, or even lethal. Excessive touchiness responses necessitate a pre-sharpened host condition.
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