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Atropine is an anticholinergic medication with therapeutic relevance that prevents the parasympathetic neurotransmitter acetylcholine from inhibiting heart rate and causing tachycardia.
Does atropine cause heart rate to rise or fall?
Atropine is a parasympatholytic drug that blocks muscarinic receptors in the cardiac sinoatrial node. This causes a substantial increase in heart rate and a decrease in heart rate variability.
Atropine blocks acetylcholine's muscarinic effects on both smooth muscles, which react to endogenous acetylcholine but are not so innervated as postganglionic cholinergic structures, and on these structures.
Atropine, a muscarinic antagonist that has the same biosynthetic route as scopolamine, is used to treat bradychardia and as a cycloplegic and mydriatic in ophthalmology.
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