Respuesta :
To carry out positive regulation of operon gene transcription, CAP and cAMP create a complex that binds the lac promoter's CAP binding site.
What is the mechanism through which CAP enhances lac operon expression?
A protein known as the catabolite activator protein has a binding site upstream of the promoter (CAP). When the CAP protein attaches, it bends the DNA, allowing the RNA polymerase to bind more efficiently, resulting in increased transcription of the lac operon.
When glucose levels in the cell fall, accumulating cAMP binds to the positive regulator catabolite activator protein (CAP), a protein that binds to the promoters of operons that control alternative sugar processing, such as the lac operon.
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