A particular oncogene with the partial mrna sequence of 5’ aug gau ggg 3’ is expressed in certain cancer cells. What partial dna sequence would be part of an effective probe to determine if this oncogene were being expressed in cells?.

Respuesta :

The partial DNA sequence that will oncogene be expressed in the cell is

5' CCC ATC CAT.

Oncogenes are a mutated form of proto-oncogenes that under normal conditions play many roles in the process of cell division or proliferation. Oncogenes in cancer cells play a role in inducing cell proliferation so that cell division becomes non-benign. In general, the action of oncogenes on cancer cells is likened to a "gas" because of the termination that induces the rate of cell proliferation.

Activation of proto-oncogenes into oncogenes is known to be a critical mechanism in cancer initiation and development. Oncogene activation will activate various signaling pathways related to cell proliferation as well as various other important steps related to carcinogeneses, such as inhibition of apoptosis, inhibition of cell differentiation, inhibition, or other processes that lead to tumor growth. Oncogene activation can also induce genetic stress that will lead to genomic instability. This will trigger the possibility of secondary mutations in cancer cells.

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