Oxidative phosphorylation takes place in mitochondrion during the electron transport chain in human cells.
Oxidative phosphorylation is the process by which ATP is formed as a result of the transfer of electrons from NADH or FADH₂ to O₂O₂ (molecular oxygen) by a series of electron carriers. The majority of the energy required in biosynthesis, preserving appropriate ion balance, and mechanical work comes from oxidative phosphorylation, which is the main source of ATP for metabolic and mechanical work. As the conversion of ADP to ATP depends on the oxidative reactions taking place in the mitochondria, this process is known as oxidative phosphorylation.
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