if we blocked all voltage-gated sodium channels in a lower motor neuron and then injected calcium into the axon terminus, the fibers in the associated motor unit would

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15-11-2022
Biology

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if we blocked all voltage-gated sodium channels in a lower motor neuron and then injected calcium into the axon terminus, the fibers in the associated motor unit would

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qwoffwhite qwoffwhite · Answer 1 · 2022-11-18T14:51:17+01:00

If we blocked all voltage-gated sodium channels in a lower motor neuron and then injected calcium into the axon terminus, the fibers in the associated motor unit would be as when calcium levels were high and acetylcholine levels were adequate, the neuron would contract.

Acetylcholine is released from synaptic vesicles that are kept in the terminal boutons of the motor neuron axon in order to transmit electrical signals to the muscles. Upon the action potential's invasion of the motor nerve terminal, voltage-gated calcium channels are opened, which causes the vesicular contents to be released into the synaptic space in a Ca2+-dependent manner.

The end plate potential is a localized depolarization caused by the activation of acetylcholine-gated ion channels (acetylcholine receptors) on the postsynaptic membrane. When it comes to the beginning and spread of action potentials in neurons and other electrically excitable cells like myocytes and endocrine cells, voltage-gated sodium channels are crucial.

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