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Molecule that is the common entry point to aerobic respiration for carbohydrates, proteins and fats : acetyl-CoA.

What is acetyl-CoA?

Acetyl-CoA is a molecule that participates in various biochemical reactions in protein, carbohydrate and lipid metabolism and it's main function is to deliver the acetyl group to citric acid cycle to be oxidized for producing energy. Basically, it is the oxidation of the acetate portion of acetyl-CoA that gives carbon dioxide and water and the energy released is then captured in the form of ATP.

Acetyl-CoA is generated by two ways:

  • by oxidative decarboxylation of pyruvate from glycolysis, which takes place in mitochondrial matrix, by oxidation of long-chain fatty acids.
  • by oxidative degradation of some amino acids.

To know more about Acetyl-CoA, refer

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