One of the two parts of the nervous system is white matter. It makes up the of the deep portions of the brain as well as the superficial portions of the spinal cord, is primarily composed of glial cells myelinated axons.
The innermost sheet-like glial activity in touch with the axon spirals around it and spins out several overlapping membrane layers to generate myelin in the PNS and CNS. Outermost and innermost layers of a myelin sheath are the only ones where cytoplasm is ejected.
Both peptidergic and nonpeptidergic C-fiber axons are found in unmyelinated, or type C, fibers, which are used for mechanical sensitivity. They are completely devoid of the myelin envelope, and the Remak fibers that are found in bundles within nerve fibers are formed by Schwann cells that surround them.
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