Gene regulation in prokaryotes: One chromosome contains all the genes. Operons are collections of genes, and many mRNA transcripts indicate many proteins. Transcription and translation occur in the cytoplasm.
Gene regulation in eukaryotes: Different chromosomes contain different genes. Introns must be cut out through mRNA splicing. Translation takes place in the cytoplasm, whereas transcription takes place in the nucleus.
Only some of a cell's genes are translated and expressed (transcribed) by the cell. By activating or deactivating the expression of the proper genes, cells respond to environmental cues. Even though all cells in the body (with a few exceptions) have the same genome, cells in different tissues and organs develop, or become specialized, by producing diverse sets of proteins in multicellular animals. These alterations in gene expression, or differences in gene expression between cells, are often controlled at the transcriptional level.
Gene expression is regulated at three main levels:
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