During early development of the vertebrate central nervous system, undifferentiated epithelial cells that enter the neuronal lineage signal to their neighbors by displaying the delta membrane proteins.
Epithelial cells are the cells that are present on the outer surface pf the body and also the internal organs like blood vessels, urinary tract, etc. Their functions can be varying like protection, secretion, absorption, excretion, filtration, diffusion, etc.
Delta proteins are the ones that participate in Notch signaling where they bind and activate another protein called the Notch protein. The role of delta protein can be seen during neurogenesis. Neurogenesis is the formation of new neurons in the body.
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