Dexmedetomidine is often used to sedate patients in critical care units (ICUs), however enteral clonidine may be a less expensive option.
This study describes how we switch a subset of adult ICU patients from dexmedetomidine to clonidine, with an emphasis on effectiveness, safety, and drug costs. From January to March 2014, we carried out a single-center prospective observational pilot research. Patients who received dexmedetomidine on successive occasions and switched to clonidine were more than 18 years old.
Dexmedetomidine maintenance, transition, clonidine maintenance, clonidine taper, and post-clonidine were the five phases that the transition evaluated in. In critically ill individuals, switching from dexmedetomidine to clonidine may be an effective, secure, and more affordable way to sustain 2A-receptor agonist therapy; these findings need to be confirmed in larger investigations.
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