Respuesta :
The blood-brain barrier requires special transporters to move amino acids and vitamins into the brain.
- The BBB divides membrane transport proteins into two groups: uptake transporters and efflux transporters.
- Multiple uptake transporters at the BBB are in charge of moving solutes from the bloodstream into the endothelial cells, where they eventually pass through the basolateral membrane into the brain.
- Passive yet saturable GLUT1 transporters that are present in both the luminal and abluminal membranes of endothelial cells mediate glucose transport across the blood-brain barrier.
- Abstract. AATs are membrane-bound transport proteins that facilitate the entry and exit of amino acids from cells or cellular organelles. AATs play a variety of physiological roles in intracellular energy metabolism, anabolic and catabolic processes, acid-base balance, neurotransmission, and other areas.
To learn more about transporters.
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