In prokaryotic cells, fimbirae are responsible for attachment to surfaces, while pilli are responsible for transfer of plasmid dna from a donor to a recipient cell.
One of the virulence components linked to colonization in both encapsulated and non-typeable strains of H is fimbriae. influenzae. The ability of the organism to haemagglutinate and attach to buccal epithelial cells was connected with the expression of these genes, which was originally discovered in type b strains.
There are four different groups of fimbriae, but only those that are long, thick, and haemagglutination-positive (LKP) mediate adhesion to human mucosal epithelial cells. Additionally, LKP fimbriae agglutinate human erythrocytes and attach to mucus. A sialic acid-containing lactosylceramide structure that is a component of the human AnWj blood type antigen was found to be the receptor accepted by this class of fimbriae, which was made easier to identify thanks to the latter characteristic.
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