14. mehran r, rao sv, bhatt dl, et al. standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the bleeding academic research consortium. circulation. jun 14 2011;123(23):2736-47. doi:10.1161/circulationaha.110.009449

Respuesta :

Organizing clinical trial processes and relative becomes difficult due to the inadequacy of standardization.

Risks of problems such as MI, stroke, stent thrombosis and death are related to bleeding complications in the patients with ACS and, coronary interventions and antithrombotics. In managing and accessing therapies, it is important to balance bleeding risks against the anti-ischemic benefits.

Trials were conducted that led to the result that improved survival is related to in reduction in bleeding. In the treatment of ACS, bleeding prevention shows good results by balancing safety. It's also found that in the bleeding definition in use there is substantial heterogeneity.

Therefore, organizing clinical trial processes like adjudication and relative becomes difficult due to inadequacy of standardization.

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