The middle cerebral artery (MCA) is the internal carotid artery's greatest terminal branch. It flows through the Sylvian (lateral) fissure before continuing to the island of Reil in a posterosuperior direction (insula).
The carotid and vertebral arteries join to form the Circle of Willis at the base of the brain. This is a network of arteries that provides several routes for blood to give oxygen and nutrients to the brain. Major arteries emerge from the Circle of Willis and go to all areas of the brain.
Two sets of arteries supply blood to the entire brain: the internal carotid arteries and the vertebral arteries. The right and left vertebral arteries join to produce a single basilar artery near the base of the brain,
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