A person with physiological dependence on a substance experiences a reduced sensitivity to its effects to the point that increased doses are needed to give the same high. This is called Pharmacodynamic interactions.
What is Pharmacodynamic interactions?
- Pharmacodynamic interactions are those in which drugs directly affect each other.
- Often, however, a pharmacodynamic interaction is really desirable if the goal is mutually potentiating effects in the same direction (synergistic effects), e.g. in the use of anti-infectives or in pain therapy. When the effect of one drug is prevented by another, the effects of these drugs are antagonistic.
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