UV radiation can directly cause the DNA within cells to mutate, which may eventually lead to the formation of cancer.

Which of the following best describe mechanisms for how UV radiation may lead to cancer?

1. Answer: CORRECT (SELECTED)
UV radiation may cause positive regulators (oncogenic) to be over-expressed.

Explanation:
If there's too much expression of positive regulators (oncogenic), there would be too much cell growth and division, a characteristic sign of cancer.

2. Answer: CORRECT (SELECTED)
UV radiation may cause negative regulators (tumor suppressors) to be under-expressed.

Explanation:
If there's not enough expression of negative regulators (tumor suppressors), there would be less tumor suppression, meaning that the likelihood of a tumor (and cancer) developing dramatically increases.

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luisvaschetto luisvaschetto · Answer 1 · 2022-08-16T19:37:40+02:00

UV radiation may both cause oncogene over-expression and tumor suppressor missexpression (under-expression).

A tumor suppressor is a gene encoding for a protein that is required to stop the cell cycle before uncontrolled cell proliferation.

For example, the p53 protein is a well-known suppressor factor that acts during apoptotic (programmed cell death) mechanisms.

On the other hand, oncogenes are expressed during tumor formation (e.g., overexpression of a growth factor).

In conclusion, UV radiation may both cause oncogene over-expression and tumor suppressor missexpression (under-expression).

Learn more about oncogenes and tumor suppressors here:

https://brainly.com/question/7276739

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