Parasympathetic neurons in the medulla respond to increased blood pressure by inhibiting the sympathetic activity.
The parasympathetic nervous system is a branch of the Autonomic Nervous System (ANS) which regulates the activity of the smooth and cardiac muscles and glands.
The presynaptic neurons of the parasympathetic system are situated within the medulla oblongata and sacral spinal cord.
During increased blood pressure, baroreceptors initiate action potentials at a higher rate and activate parasympathetic stimulation of the heart.
Consequently, cardiac output drops down and sympathetic stimulation of the peripheral arterioles also reduces leading to vasodilation. Both these activities help in reducing the blood pressure.
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