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Because bacteria's chromosomes lack telomeres, they do not require telomerase. The majority of bacterial chromosomes are circular, which means they are without ends. This indicates that DNA polymerase is capable of copying a whole chromosome without erasing any data.

In comparison to eukaryotes, bacteria typically have significantly smaller chromosomes. All of their genes and genetic material can fit onto a single chromosome, which has no start or stops. Closed circular DNA is what is known as a bacterial chromosome.

An enzyme called telomerase aids in the restoration of telomeres, the ends of chromosomes that break down during cell replication. Due to their uncontrollable replication, cancer cells frequently have an overabundance of telomerase.

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