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The RNA polymerase sigma (s) subunit separates from the core enzyme after transcription starts and the RNA chain has gained roughly 10 nucleotides.

Result for an image When does the RNA polymerase sigma (σ) component separate from the main enzyme?

Sigma's (σ) Function in Transcription

At the onset of elongation or at a later point after transcription begins, the factor separates from the core polymerase, leaving the core enzyme to complete elongation. Bacterial RNA polymerase's main enzyme is made up of five subunits: two plus two, two plus two, and two plus one . The catalytic site of the enzyme is made up of the - and -′ subunits. The -subunit is necessary for both promoter recognition and assembly.

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