Respuesta :
The correct option is (A) Abatacept and Alefacept
Abatacept and Alefacept directly act on immune cells by inhibiting their interaction for further process of immunity.
How Abatacept and Alefacept act on immune cells?
- Abatacept (CTLA-4-Ig) prevents B7, which is expressed by antigen-presenting cells, from interacting with CD28, which is expressed by T cells.
- This medication is used to treat psoriasis and rheumatoid arthritis. Recombinant CD58-IgG fusion protein alefacept (Amevive) prevents CD2 on T cells from interacting with CD58 (LFA-3) on antigen-presenting cells.
- Alefacept specifically targets memory T cells through the inhibition of the CD2 co-stimulatory pathway, in contrast to abatacept, which blocks naive T-cell activation.
Learn more about the immune cells with the help of the given link:
https://brainly.com/question/9924784
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I understand that the question you are looking for is "Which two drugs work by blocking of costimulatory pathways that activate lymphocytes?
A. Abatacept and Alefacept
B. Efalizumab and Ntalizumab
C. Abatacept and Ntalizumab
D. Alefacept and Efalizumab"
