Calcitonin release is no longer stimulated, which stops bone cells from releasing calcium into the blood.
Calcitonin secreted when blood calcium levels drop too low because when levels of calcium in the blood decrease, the amount of calcitonin secreted is also decreased. The secretion of calcitonin is also inhibited by the hormone somatostatin, which can also be released by the C-cells in the thyroid gland.
Calcitonin is also responsible for effecting of parathyroid hormone (PTH), which acts to increase the blood calcium level. Calcitonin lowers blood calcium levels by suppressing osteoclast activity in the bones and increasing the amount of calcium excreted in the urine.
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