Leptin is extensively used as a key controller of metabolic function, including important modulatory activities on the innate and adaptive immune responses.
Leptin is a 16 kDa non-glycosylated protein that is mainly produced by adipocytes.
Leptin has a dual role as a hormone and a cytokine. As hormone, it influences multiple endocrine functions and bone metabolism, in addition to the key function of modulating energy homeostasis like thermoregulation.
As a cytokine, leptin promotes inflammatory responses. Elevated levels of circulating leptin in obese patients make them more susceptible to develop cardiovascular/degenerative diseases, in addition to autoimmune disease.
To learn more about leptin and its dual roles, here
brainly.com/question/21052241
#SPJ4
