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Two noncellular agents, smaller than viruses, are infectious RNA strands called virioids and infectious proteins called prions.

Virioids are irresistible specialists that comprise just of bare RNA with next to no defensive layer, for example, a protein coat. Viroids contaminate plants and are reproduced to the detriment of the host cell. Viroid genomes are little single-stranded circles of RNA that are just 250-400 bases in length.

A prion is a "proteinaceous infectious particle," a name that was abbreviated to "prion" simply a protein. Prions are proteins that can attack cells and some way or another direct their own duplication, making a greater amount of the separated proteins. Prions can enter the cerebrum through contamination, or they can emerge from mutation in the gene that encodes the protein.

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