The action potential causes information to be transmitted from the axon of the first neuron (presynaptic neuron) to the dendrites or cell body of the second neuron (postsynaptic neuron) by secretion of chemicals called neurotransmitters.
How do synaptic transmissions occur?
- Synapse is the junction between neurons where information gets exchanged.
- The axon of the presynaptic neuron does not actually touch the dendrites of the postsynaptic neuron and is separated from them by a space called the synaptic cleft.
- Stimulation of the presynaptic neuron to produce an action potential causes the release of neurotransmitters into the synaptic cleft.
- Neurotransmitters are stored in small vesicles located in knoblike structures on the axon tips.
- Most of the released neurotransmitters bind with molecules at the receptors on the dendrites of the postsynaptic neuron.
- The combination of the neurotransmitter molecules to receptor cell molecules in the postsynaptic cell membrane produces a change of potential in the postsynaptic cell membrane called the postsynaptic potential (PSP).
- Thus a signal is caused on a postsynaptic neuron.
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