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Cancer takes time to grow because it is the culmination of a series of genetic and genomic changes called Mutations that enable certain cells to divide more frequently than normal.
What Are Mutations?
- Changes to an organism's DNA sequence are referred to as mutations. Mutations can be the result of viral infection, exposure to mutagens, or mistakes in DNA replication during cell division.
- Somatic mutations—those that take place in body cells—cannot be passed on to progeny, whereas germline mutations—those that happen in eggs and sperm—can.
- Mutagens are environmental elements that trigger mutations.
- Radiation, substances, and infectious diseases are a few examples of mutagens. The nature of mutations may be spontaneous.
- TP53, a gene that generates a protein that inhibits the development of tumors, is the gene that is most frequently altered in all malignancies.
- In addition, this gene's germline mutations can result in Li-Fraumeni syndrome, a rare, inherited condition that increases the risk of getting some malignancies.
To learn more about Mutations refer to:
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