If you observe the activity of methylated DNA, you would expect the change in the activity of DNA molecule.
DNA methylation is a process by which methyl is added to the DNA molecule which can change the activity of a DNA without changing the sequence. When it is located in a gene promoter, DNA methylation acts to repress gene transcription.
So we can conclude that If you observe the activity of methylated DNA, you would expect the change in the activity of DNA molecule.
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