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Antigen-presenting cells

Antigen-presenting cells (commonly abbreviated to APCs) are a vastly varied group of white blood cells that take part in the immune response by processing antigens to present to T cells, so the latter can recognize the threat and carry a response.

B lymphocytes are immune cells capable of producing antibodies to attack foreign threats (this is called humoral immune response), for this to be possible, B cells need to be previously activated by T-cells.

But B cells can also act as antigen-presenting cells when the antigen is a molecule simple and repetitive in structure, and capable of evoking an immune response without the participation of T cells (T-cell-independent antigen). This response will consist of antibodies production as well.

T-cell-independent antigens

There are two types of T-cell-independent antigens (TI):

  • TI-1 antigen: can activate B cells directly.
  • TI-2 antigen: its highly repetitive structure generates multiple cross-linking of B cell receptors (BCR), thus triggering its activation.

In conclusion, B cells can act as APCs when the antigen is T-cell-independent.

To learn more about the immunity, read here:

https://brainly.com/question/11101746