Marfan syndrome of is a multisystem disorder that is the result of impaired fibrillin synthesis, fibrillin is usually found in abundance in the connective tissue of the aorta.
It is related to connective tissue disorders that at the cardiac level, it can cause stretching or weakening of the aorta.
Its inheritance pattern is autosomal dominant, although it originates from spontaneous mutations, in up to 25% of cases.
Therefore, we can conclude that Marfan syndrome of is a multisystem disorder that is the result of impaired fibrillin synthesis, fibrillin is usually found in abundance in the connective tissue of the aorta.
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