General transcription factors are highly specialized proteins that are required for RNA pol II activation.
They are proteins also known as basal transcription factors that recognize specific DNA sequences in the regulatory region of all genes.
These are capable of interacting with the transcription pre-initiation complex to induce or inhibit the activity of the enzyme RNA polymerase II.
Therefore, we can conclude that the general transcription factors are proteins that allow the assembly of RNA Polymerase II and the initiation of transcription.
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