Tay sachs disease is caused by a mutation in the hexa gene. There are a number of mutations that are known to cause the symptoms of tay sachs. What kind of mutation is presented in this interactive?.

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XxMikeLearnsxX1404 XxMikeLearnsxX1404

14-03-2022
Biology

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Tay sachs disease is caused by a mutation in the hexa gene. There are a number of mutations that are known to cause the symptoms of tay sachs. What kind of mutation is presented in this interactive?.

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luisvaschetto luisvaschetto · Answer 1 · 2022-03-28T13:21:52+02:00

Tay Sachs disease is caused by a type mutation called frameshift mutation. It alters all protein sequence downstream of the mutation site.

What is a mutation?

A mutation is any alteration in the genetic material (DNA) of the genome of a particular organism.

A frameshift mutation is a type of mutation capable of changing all the Open Reading Frame (ORF) of a protein, thereby altering its functional and structural properties.

Tay Sachs disease is caused by a frameshift mutation in the HEXA gene located on chromosome 15, which leads to a defective protein and faulty cellular transport of beta-hexosaminidase.

Learn more about frameshift mutations here:

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