The choice that best supports an interpretation is : ( E ) “When are you coming?” (paragraph 5)
Speculation is the formation of a theory or feeling without concrete affirmation, the choice of words that suggests that the adult narrator speculates about his mother is "When are you coming " because the narrator does not have an affirmative resolve, he therefore conveys his feelings through those words.
Hence we can conclude that the choice that best supports an interpretation is when are you coming
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Options related to your question is missing and attached below are the options
A."why this picture" (paragraph 3)
B. "Courage alone could not get me past that heavy door” (paragraph 4)
C. “But for a four-year-old, everything is sacred and ordinary” (paragraph 5)
D. “the metaphors of her faith were also the metaphors of medicine” (paragraph 5)
E. “When are you coming?” (paragraph 5)