The first time Burr made Hamilton angry, according to americanhistory.com, was:
"The rivalry between Alexander Hamilton and Aaron Burr had its roots in a 1791 Senate race. Aaron Burr defeated Philip Schuyler who was Hamilton's father-in-law. Schuyler as a Federalist would have supported George Washington'sand Hamilton's policies while Burr as a Democratic-Republican opposed those policies."
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