The brain region that plays a key role in integrating information and sending appropriate signals to autonomic centers is the amygdala. The amygdala receives sensory information from multiple pathways.
The amygdala, also known as the 'fear center' is located in the medial temporal lobe.
The amygdala receives sensory information from subcortical and cortical processing pathways, which is associated with the threat, and then orchestrates reactions by controlling the autonomic center.
The amygdala is involved in the perception of different emotions (e.g., anger, fear, sadness, etc).
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